Government funds ground-breaking research
A Royal Perth Hospital immunologist investigating the possibility of using an antibody to trigger natural immune responses to fight HIV
Vaccines
Vaccines are substances pretending to be infections. They train the immune system so that when a real infection comes along, the immune system is primed and ready to respond effectively. In HIV research, vaccines can be therapeutic (i.e. training your immune system to be more effective even if you are already HIV+) and/or preventative (i.e. training your immune system to block HIV infection altogether).
Broadly neutralizing antibody 8ANC195 recognises closed and open states of HIV-1 Env
Highlights •3.58 Å structure of 8ANC195-Env trimer defines the gp120-gp41 site of HIV vulnerability •EM structure shows 8ANC195 binds Env trimer