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Miranda Smith

Rousing the reservoir: understanding more about where HIV hides in lymph nodes

4 years ago HIV Cure Community Partnership Reservoir, Remission, Rebound

Sydney researchers are leading a study to discover more about the HIV reservoir. The TRESAX study seeks to find out where HIV rebounds from during treatment interruption and what impact vaccination has on virus rebound. The work is led by Kirby Institute Director Professor Tony Kelleher and research fellow Dr Mee Ling Munier. The study…

Miranda Smith

The promise and challenge of stem cell transplants in HIV cure

4 years ago HIV Cure Community Partnership Novel Approaches, Reservoir, Remission, Rebound

The only confirmed case of HIV cure, and two cases of long-term remission without treatment, are the result of stem cell transplants. In this article, we delve into the world of stem cell transplants and how they are being used in people living with HIV. To help, we have developed a transplantation glossary to explain…

Miranda Smith

Doing FLIPS: a new way to find latent HIV

6 years ago HIV Cure Community Partnership Reservoir, Remission, Rebound

Researchers have revealed a new way to understand the HIV that stays in the body during therapy. The group from Sydney’s Westmead Institute for Medical Research have developed a technique for detailing HIV at a molecular level. Bonnie Hiener and colleagues, led by Associate Professor Sarah Palmer, published the study in the journal Cell Reports…

Searching for hidden HIV

7 years ago NAPWHA Novel Approaches

Attempts to cure HIV have been thwarted by a particular type of immune-system cell that can hide the virus. These long-lived infected T cells can evade detection by the body for years, and are hard to find, study and kill. Reliably identifying these covert reservoirs is top of the wish-list for HIV researchers, but they’ve…

Miranda Smith

Engineered T cells show promise in fight against HIV

7 years ago HIV Cure Community Partnership Novel Approaches

T cells that target HIV but are resistant to HIV infection are the latest strategy in the battle against HIV. Chimeric antigen receptor (CAR)-T cells are a concept also in development for treating cancer. Seattle researchers have published a new approach for developing CAR-T cells. This new strategy could eventually lead to better outcomes for people…

Christopher Kelly

HIV-1 genomes eliminated from T cells

8 years ago NAPWHA Gene Therapy

Scientists at the Lewis Katz School of Medicine at Temple University in Philadelphia have designed a gene-editing system that may hold the answer for an eventual cure for people living with HIV. The study — published in the Nature journal Scientific Reports — explains how researchers have eradicated the virus from human cell DNA. “The…

Inclusion, Respect, Equity: A photo essay of people participating in HIV cure research at The Alfred ...

This beautiful photographic essay was compiled by The Alfred in Melbourne, and all credit for this article goes to their amazing teams and the people they care for. This article is shared with permission of The Alfred.

Alfred Health

Working together with researchers and clinicians at The Alfred, members of the community of people living with HIV in Victoria have been integral to progressing ...

Trust crucial to treatment interruption

Gene therapy advance in mice

New sequencing method shows many blood-derived HIV particles are defective

High CD4 count before HIV treatment contributes to smaller HIV reservoir on ART

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Supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number U19AI096109. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Founded in 1989, The National Association of People with HIV Australia (NAPWHA) is Australia’s peak non-government organisation representing community-based groups of people living with HIV (PLHIV).
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