By Jeffrey Laurence, M.D., and Rowena Johnston, Ph.D
Division or Multiplication: Exploring the Maintenance of the HIV Reservoir
The remarkable stability of the reservoir of latent HIV in a patient on effective antiretroviral therapy (ART) is measured in many decades. But the mechanisms by which this is achieved are under debate. Two possibilities are: 1) the viral reservoir may maintain its size by infected cells continuing to produce virus that infects other cells…