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Matthew Pitman

Vitamin D3 affects the HIV reservoir in humans

2 years ago HIV Cure Community Partnership Research Spotlight

Thirty PLHIV in Melbourne took part in the randomised, placebo-controlled VIVA trial. Researchers looked to see if 24 weeks of high dose vitamin D3 could reduce the amount of HIV that persists on ART. After 24 weeks, there was no change in HIV DNA. Encouragingly though, there was a reduction in total HIV DNA 12…

Miranda Smith

Rousing the reservoir: understanding more about where HIV hides in lymph nodes

4 years ago HIV Cure Community Partnership Reservoir, Remission, Rebound

Sydney researchers are leading a study to discover more about the HIV reservoir. The TRESAX study seeks to find out where HIV rebounds from during treatment interruption and what impact vaccination has on virus rebound. The work is led by Kirby Institute Director Professor Tony Kelleher and research fellow Dr Mee Ling Munier. The study…

Miranda Smith

Gut feeling for a functional cure

7 years ago HIV Cure Community Partnership Novel Approaches

HIV infection takes a heavy toll on the gut. The virus enters the body and heads straight for the stomach and intestines. This is harmful, destroying most of the immune cells that live in the gut. This early damage sets the scene for some of the big problems of ongoing HIV infection. One of these…

Christopher Kelly

HIV-1 genomes eliminated from T cells

8 years ago NAPWHA Gene Therapy

Scientists at the Lewis Katz School of Medicine at Temple University in Philadelphia have designed a gene-editing system that may hold the answer for an eventual cure for people living with HIV. The study — published in the Nature journal Scientific Reports — explains how researchers have eradicated the virus from human cell DNA. “The…

aidsmeds

Gene Therapy Controls HIV Longer Than Four Months in Study

8 years ago NAPWHA Gene Therapy

Sangamo Biosciences’ efforts to develop genetic therapies for HIV have had some early success, with two of three participants in one cohort maintaining control of the virus for an extended period during which they were not taking standard antiretroviral (ARV) treatment. The biotech company is conducting a Phase I/II study, known as SB-728-1101, of its…

Inclusion, Respect, Equity: A photo essay of people participating in HIV cure research at The Alfred ...

This beautiful photographic essay was compiled by The Alfred in Melbourne, and all credit for this article goes to their amazing teams and the people they care for. This article is shared with permission of The Alfred.

Alfred Health

Working together with researchers and clinicians at The Alfred, members of the community of people living with HIV in Victoria have been integral to progressing ...

Trust crucial to treatment interruption

Gene therapy advance in mice

New sequencing method shows many blood-derived HIV particles are defective

High CD4 count before HIV treatment contributes to smaller HIV reservoir on ART

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Supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number U19AI096109. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

About NAPWHA

Founded in 1989, The National Association of People with HIV Australia (NAPWHA) is Australia’s peak non-government organisation representing community-based groups of people living with HIV (PLHIV).
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