This beautiful photographic essay was compiled by The Alfred in Melbourne, and all credit for this article goes to their amazing teams and the people they care for. This article is shared with permission of The Alfred. Working together with researchers and clinicians at The Alfred, members of the community of people living with HIV…
Drs Jesper D. Gunst PhD, Thomas A. Rasmussen PhD and Ole S. Søgaard PhD of Aarhus University Hospital, Denmark share the results of the TITAN study exploring bNABs towards an HIV cure with NAPWHA, ahead of publication in Nature Magazine on the 11th of September. The TITAN study is the first HIV cure study of…
Dr Jillian Lau of the Doherty Institute and Alfred Health in Melbourne attended the recent IAS (International AIDS Society) HIV Cure and Immunotherapy preconference in Brisbane. Dr Lau also acted as rapporteur for the preconference, along with Ellen Bowden-Reid, a PhD candidate from the Kirby Institute, Sydney. Dr Lau has kindly compiled this report for…
HIV is a virus that inserts its own DNA into the host DNA upon infection. This “provirus” can remain dormant, or latent, for a long time. Proviruses are the source of new viruses causing viral rebound if antiretroviral therapy (ART) is stopped. This means treatment is a lifelong proposition for people living with HIV (PLWH)….
As the search for the elusive cure for HIV continues, researchers must take a lesson from the humble car safety airbag. Just like the airbag, HIV impacts women differently to men. The well-intentioned scientists who first developed the airbag initially tested it against crash test dummies based on the “average-sized male”. In the real world…
In the winter issue of Positive Living we’ve four takeaways from CROI — plus why talk of a cure is premature. In an era of U=U and TasP, we ask: are the long-term survivors the forgotten generation? Meanwhile, David Menadue reviews two films that portray the early days of HIV; Dr Louise returns with What’s…
In the spring issue of Positive Living, all things AIDS 2018. We’ve an overview of the conference itself, and antipodean activists and advocates share their impressions. We report from Indonesia, where the country’s anti-LGBT agenda is having a devastating impact on its HIV response. To mark 30 years since the introduction of AZT to Australia,…
Does immune checkpoint blockade have indirect effects on cells other than CD4 T cells? Filippos Porichis and colleagues have studied this question in a series of experiments on cells from people living with HIV. They show that blocking both PD-1 and IL-10 restores function to helper CD4 T cells. These reinvigorated helper cells can then…
New research suggests that the estrogen receptor (ESR-1) is important in controlling HIV latency. In lab models of latent HIV and in cells from people living with HIV, researchers studied the effects of compounds binding to ESR-1. The sex hormone estradiol strongly blocked HIV reactivation. Non-hormonal drugs that bind ESR-1 were weak HIV activators that…
Researchers have discovered a type of antibody that blocks normal immune responses in chronic HIV infection. NIH researchers studied blood samples from people at different stages of HIV infection and compared them with samples from people without HIV. They found that a type of antibody called immunoglobulin G3 (IgG3) hangs around in the blood of…
This beautiful photographic essay was compiled by The Alfred in Melbourne, and all credit for this article goes to their amazing teams and the people they care for. This article is shared with permission of The Alfred.
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Working together with researchers and clinicians at The Alfred, members of the community of people living with HIV in Victoria have been integral to progressing ...
