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Brent Allan

INSPIRING a new generation of community-minded HIV researchers

5 years ago HIV Cure Community Partnership Community

A new project seeks to put the principles of community involvement in research into action. The INSPIRE project has been funded through the Melbourne HIV Cure Consortium in Melbourne, Australia. International best practice, and the United Nations, endorse the principles of Greater Involvement of People with HIV and AIDS (GIPA). GIPA emphasises the ethical and practical…

What should a functional cure for HIV aim to do?

5 years ago HIV Cure Community Partnership Research Spotlight

What might a functional cure for HIV look like? In a recent study, researchers assumed that HIV reactivation from latency occurs about once per week. They assessed three cure strategies: reducing the HIV reservoir, removing susceptible targets and eliciting immune control. A 1000-fold reservoir reduction would delay viral rebound by 20 years if treatment stopped….

Combination strategy delays virus rebound in monkeys

5 years ago HIV Cure Community Partnership Research Spotlight

Harvard researchers have published exciting results on a combination approach to tackling latent HIV. In a monkey model of HIV infection, the group combined the innate immune activating compound GS-9620 (a toll-like receptor 7 agonist) with the broadly neutralising antibody PGT121. The combination was given while infected monkeys were on treatment. When treatment stopped, the…

Miranda Smith

Don’t believe the hype: Gammora is not an HIV cure

5 years ago HIV Cure Community Partnership Community, Media

With the internet and a twitter account, spreading information is easy. When it comes to HIV cure research, it can be hard to distinguish genuine, good quality science from spin-doctored, over-hyped attention seeking. The story of ‘Gammora’ is a cautionary tale. Flood of false claims Towards the end of October, an Israeli company, Zion Medical,…

Miranda Smith

Hide and seek: new trial to help find hidden HIV

5 years ago HIV Cure Community Partnership Get Involved, Reservoir, Remission, Rebound

HIV plays a game of hide and seek during treatment. Australian researchers have launched a new study to find a better way to see hidden HIV. They hope to develop a non-invasive way of measuring the HIV that remains in the tissues of people on antiretroviral treatment. Why do we need a better way to…

New light on tricky HIV structure

5 years ago HIV Cure Community Partnership Research Spotlight

New details have emerged of the exact structure of an important HIV vaccine target. The membrane-proximal external region (MPER) is a part of the HIV envelope protein. Broadly neutralising antibodies in people with HIV often target the MPER. A clearer view of the MPER shape and structure could help make vaccines that target this area….

Timothy Krulic

Joining the Search for a Cure

5 years ago HIV Cure Community Partnership Community, Novel Approaches

This article was originally published in the Spring 2018 issue of Poslink, the newsletter of Living Positive Victoria. Have you ever wondered what it’s like to be part of a clinical trial for a cure for HIV? Although antiretroviral therapy means that people living with HIV (PLHIV) in many countries have similar health outcomes and…

Miranda Smith interviews Jintanat Ananworanich

Stigma, seroconversion and the search for an HIV cure

5 years ago HIV Cure Community Partnership Reservoir, Remission, Rebound

Reducing the persistent stigma and discrimination related to HIV infection drives clinician scientist Jintanat Ananworanich. Her research interests range from HIV infection in children to dissecting the very early stages of HIV infection in adults. We caught up with Dr Ananworanich while she was in Melbourne to deliver a public lecture at the Doherty Institute….

Immune profiling tool to identify exhausted cells

5 years ago HIV Cure Community Partnership Research Spotlight

T cell exhaustion is a type of immune dysfunction that occurs in cancer and chronic infections. Most exhausted T cells express common markers, but not all exhausted cells respond to immunotherapy. Bengsch and colleagues have developed an immune profiling tool to identify subsets of exhausted T cells. Their strategy was developed by comparing exhaustion genes…

Read the spring issue of Positive Living here

5 years ago NAPWHA Community

In the spring issue of Positive Living, all things AIDS 2018. We’ve an overview of the conference itself, and antipodean activists and advocates share their impressions. We report from Indonesia, where the country’s anti-LGBT agenda is having a devastating impact on its HIV response. To mark 30 years since the introduction of AZT to Australia,…

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Inclusion, Respect, Equity: A photo essay of people participating in HIV cure research at The Alfred ...

This beautiful photographic essay was compiled by The Alfred in Melbourne, and all credit for this article goes to their amazing teams and the people they care for. This article is shared with permission of The Alfred.

Alfred Health

Working together with researchers and clinicians at The Alfred, members of the community of people living with HIV in Victoria have been integral to progressing ...

Trust crucial to treatment interruption

Gene therapy advance in mice

New sequencing method shows many blood-derived HIV particles are defective

High CD4 count before HIV treatment contributes to smaller HIV reservoir on ART

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Supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number U19AI096109. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

About NAPWHA

Founded in 1989, The National Association of People with HIV Australia (NAPWHA) is Australia’s peak non-government organisation representing community-based groups of people living with HIV (PLHIV).
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